PMC

Granulocyte frequencies. Percentage of eosinophils (A) and neutrophils (B) relative to the total number of WBC in STH− and STH+ subjects (left) and in STH− and Al+, Hw+, and Tt+ subjects (right). Counts at baseline are shown with geometric means and 95% CIs (STH−, n = 73; STH+, n = 118; Al+, n = 42; Hw+, n = 81; Tt+, n = 61). The effect of anthelmintic treatment on eosinophil (C) and neutrophil (D) counts is displayed with 95% CIs (n = 195). Differences between STH− and STH+ subjects were tested with Student t test. Differences between STH−, Al+, Hw+, and Tt+ subjects were tested with ANOVA followed by a Dunnett multiple comparison test. Treatment effect was assessed using mixed models (see Methods). *P < .05; **P < .01. Abbreviations: CI, confidence interval; NS, not significant; STH, soil-transmitted helminths; Al, Ascaris lumbricoides; Hw, hookworm; Tt, Trichuris trichiura; WBC, white blood cells.

All 3 parameters were significantly different between the TH and STH groups (see Results). Horizontal lines depict the mean within a group.

Eosinophil granule proteins. Major basic protein (MBP), eosinophil cationic protein (ECP), and eosinophil derived neurotoxin (EDN) concentrations in serum at baseline (A) and the effect of albendazole treatment (B) are shown. A, Lines represent geometric means and 95% CIs (STH−, n = 116; STH+, n = 168). B, The effect of anthelmintic treatment is displayed with 95% CIs (n = 299). Differences between STH− and STH+ subjects were tested with Student t test. Treatment effect was assessed using mixed models (see Methods). Abbreviations: CI, confidence interval; NS, not significant; STH, soil-transmitted helminths.

A. (a) occipital view of NMB Sth. 833; (b) same as a with labelling of anatomic features; (c) focus on postorbital bar of NMB Sth. 833; (d) focus on foramina for the nervus hypoglossus of NMB Sth. 833; see for abbreviations.